JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY    Abstract   Diuretics represent a large and heterogeneous class  of drugs, differing from each other by structure, site and mechanism of  action. Diuretics are widely used, and have several indications in  different cardiovascular disorders, particularly in hypertension and  heart failure.   Despite the large number of available  anti-hypertensive drugs, diuretics remained a cornerstone of  hypertension treatment. In the current editorial, we assessed the actual  place of different diuretics in the hypertension guidelines focusing on  the concept of tailored approach in prescribing them for hypertensive  patients.    Keywords: Diuretics; Hypertension; Hydrochlorothiazide; Indapamide; Guidelines   Introduction   Diuretics represent a large and heterogeneous class  of drugs, differing from each other by structure, site and mechanism of  action. Diuretics are widely used, and have several indications in ...