Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Background: Youth of 18 to 20 year age achieve medical college admission through tough competition. Genotype, phenotype and environmental interactions that drive cardiovascular and other lifestyle diseases may be meaningfully recognized at such stage. Early detection of lifestyle disease and its determinants can guide timely interventions and correction toward prevention/reduction of morbidity and mortality. Objective: Screening of first year male and female medical students for pre-hypertension and a study of family history, clinicodemographic and biochemical characteristics in comparison with normotensive peers. Method: In a cross sectional study, 23 subjects (16 males and 7 females) in 18-20 year age range found to be prehypertensive upon screening were compared with 15 mached normotensive peers(10 males and 5 females). Familial, psychological behavioral, clinicodemogra...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Coronary Artery Disease (CAD) is one of the leading causes of morbidity and mortality in the world. Detection as well as modification of risk factors for cardiovascular disease (CVD) has been the topics research over several decades. Multiple drugs have been studied and used in clinical practice with people seeking “natural” alternatives. When evaluating for optimal treatment options and the multiple risk factors associated CAD (e.g. diabetes, hypertension, etc.), garlic can play a prominent role. Studies have shown promising results in treating hypertension, altering the lipid profile, prevention and even treatment of coronary atherosclerosis and its systemic anti-oxidant properties. Garlic also has positive effects outside the cardiovascular system (e.g. immune system). It can be used stand-alone or as an adjunct to current medical therapy. No clinically significant side...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Introduction In the continuously evolving efforts to provide optimum revascularization for high risk Critical Limb Ischemia patients, vascular surgeons around the world have widely adopted hybrid approach. This combination of the advantages of open and endovascular techniques allows the implementation of tailored complex multi-level reconstruction plans usually within a single setting [1-3]. What started over 40 years ago, with the combination of simple iliac angioplasty and femoro-femoral bypass [4] is gradually increasing in complexity & becoming a widely accepted therapeutic option. Furthermore, the increasing sophistication of minimally invasive endovascular techniques with successful treatment of multi-segmental lesions has contributed to a reduced morbidity & duration of hospital stay when Hybrid revascularizations are performed [5]. The final benefit thus is full reva...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Premature atherosclerotic cardiovascular disease (CVD) is a well known complication of diabetes mellitus (DM) associated with significant morbidity and mortality. The development of atherosclerosis is largely promoted by oxidative stress and chronic inflammation. Elevated low-density lipoprotein (LDL) is a known atherosclerotic risk factor but LDL must be modified to become atherogenic. Inflammatory-derived reactive oxygen and nitrogen species oxidize LDL (oxLDL) giving rise to lipid peroxides and aldehydes that favor the initiation and progression of atherosclerotic lesions. Beta-2-glycoprotein I (β2GPI) is a lipid binding plasma protein with pleiotropic functions that binds oxLDL via specific oxidative-derived ligands to form pro-atherogenic oxLDL/β2GPI complexes and in this guise exerts a buffering effect upon LDL oxidation. Statin (Rosuvastatin) treatment lowered serum le...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Background: Depression is disturbance of mood, speech and thoughts interfering with the individual’s social life and negatively affecting the family and thus the whole society. Suicide is the most horrible complication ending the life of the patient. Escitalopram belongs to the SSRIs, the most commonly used group of antidepressants worldwide. Objective: To explore the effects of Escitalopram treatment on lipid profile in patients with depression. Methodology: This experimental study of 6 months duration was conducted in Sir C.J Institute of Psychiatry Hyderabad and Isra Research Laboratory from July 2016 to December 2016. 72 diagnosed patients of depression were selected through non probability purposive sampling. After ethical approval and informed consent blood sample were collected under a septic measures. Samples were analyzed for total cholesterol, HDL, LDL and TAGs...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Various studies showed the possibility of the Risk Factors to promote a disease in the arterial wall and the following development and progression of the Atherosclerosis with its impact on future vascular events. The early stage of atherogenesis is the atherosclerotic plaque, and the primary-prevention had already proved itself efficacius in this early stage, because its erosion and rupture can lead to thrombus formation on the site of the plaque and vessel occlusion, culminating in Cardiovascular disease (CVD) with a variety of clinical manifestations. The most significant clinical manifestation, in terms of morbility and mortality, is CHD. The aim of the primary-prevention, dietary and lifestyle changes is the regression or slow-down and stability of atherosclerotic plaques, with the control of cardiovascular risk factors. Cardiovascular Risk Various studies showed ...