Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract The use of prostaglandin E1 in peripheral occlusive arterial disease is an option for patients for who interventional options are not present. This study assessed the patient reported outcomes and perception of benefits of infusion therapy. 30 patients who completed their 5th month of infusional therapy were included in the study. 3 patients had major lower extremity amputations, 13 had minor lower extremity amputations during the course of infusion therapy. The mean visual analogue scale score prior to treatment was 8.5 prior to treatment and the VAS score was 6.2 post infusion. All patients were satisfied to continue their treatment with PGE1 and perceived a benefit from the therapy. Thus infusional PGE1 is a therapeutic option for patients in whom revasularisation options are not available. Keywords: Prostaglandin E1; Peripheral vascular disease; Outcome ...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Opinion The pooled analysis of Mente et al. [1] concludes: “Compared with moderate sodium intake, high sodium intake is associated with an increased risk of cardiovascular events and death in hypertensive populations, while the association of low sodium intake with increased risk of cardiovascular events and death is observed in those with or without hypertension. These data suggest that lowering sodium intake is best targeted at populations with hypertension who consume high sodium diets”. The article “Measurement Matters” [2] challenges potentially biased sodium measurements in the pooled analysis of Mente [1] and cite “a study involving CKD patients that used the average of three nonconsecutive 24-hour urine collections (that) revealed a strong linear association between higher urinary sodium excretion and an increased risk of CVD” [3]. In this prospective cohort study of pa...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Several studies indicate that psychological factors strongly influence the neuro hormonal and behavioral cardiovascular risk factors and the course of coronary artery disease and event onset. New epidemiologic evidence for the association between psychosocial risk factors and coronary artery disease identifies pathologic mechanisms that may be responsible for this association. Not much attention is paid to finding and managing the stressing factors that provoke psychological distress and then multiple adverse peripheral effects. This short review highlights a new way to look at the behavioral risk factors; putting attention to what there is behind the onset of stress and psychological distress that are related with cardiovascular risk factors, atherosclerosis and events. The role of cardiologist in finding out, assessing and managing stressors and behavioral risk factors is em...