Posts

Showing posts with the label Fibrosis

Endomyocardial Fibrosis Secondary to Filariasis - A Vanishing Syndrome-Juniper Publishers

Image
JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract A 70-year-old gentleman presented with 8 months history of low grade fever and dyspnoea on exertion which worsened gradually. It was not associated with history of cough, weight loss and pedal edema. There was no prior significant chronic illness including bronchial asthma. Laboratory work-up revealed raised total leukocyte count with hypereosinophilia. Chest radiograph, lower limb venous Doppler, and computed tomography pulmonary angiogram were normal. Genetic testing for chronic eosinophilic leukemia was negative. However, IgG and IgM antibodies to filaria were raised. Echocardiogram showed right ventricular apical obliteration due to thrombus. Patient was started on Diethylcarbamazine and oral anticoagulants. He responded very favourably to treatment with improvement in symptoms, normalization of eosinophilia, and complete resolution of right ventricular apical throm...