Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Diabetes mellitus is recognized by WHO experts as a non-communicable epidemic and represents a serious medical and social problem. In 2012, suffered of diabetes mellitus about 6.4% (285 million) of the world’s inhabitants. By 2030, the number of patients is expected to increase to 7.7% (439 million people) [ 1 ]. Coronary heart disease is the leading cause of death in patients with diabetes [ 2 ], with 90% of these patients suffering from type 2 diabetes (diabetes mellitus 2) [ 3 ]. Keywords: Breast cancer; Oncogynaecology; Gynaecology; Oncology; Surgery Introduction The presence of diabetes is associated with the emergence of all forms of coronary heart disease - angina pectoris, painless myocardial ischemia, myocardial infarction, sudden cardiac death [ 4 ]. At the same time, macrovascular complications, including coronary hear...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Background: Diabetes mellitus (DM) is a known major cardiovascular risk factor, early detection of left ventricular (LV) subclinical dysfunction is important to prevent overt heart failure in diabetic patients, this study aims to evaluate the regional and global LV myocardial functions by Strain and strain rate echocardiography in asymptomatic patients with type 2 DM. Patients and methods: The study included 38 asymptomatic type 2 DM patients with preserved ejection fraction (EF)>50%, excluding those who had hypertension, valvular, coronary artery disease, arrhythmias or conduction delay, they were compared to 20 healthy subjects as control group, color tissue Doppler imaging (TDI) was acquired in apical 4, 2 and 3-chamber views and LV regional and global peak systolic longitudinal strain(PSLS) and peak systolic strain rate(PSSR) were measured for 16LV segments. Results: ...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Introduction and objective: Coronary calcium score (CCS) determined through multiple detector computed tomography is an excellent non-invasive method for detecting coronary atherosclerosis in subclinical stages. In this study we evaluated the presence of coronary artery disease in the subclinical stage by means of the coronary calcium score in diabetic patients. Methods: Cross-sectional descriptive study in diabetic patients with 10 years or more from it evolution and without coronary disease symptoms. We included different variables such as: demography (age, sex), clinics (smoking habit, alcoholism, and history of hypertension, type of diabetes and evolution's time), and anthropometrics (body mass index), hemoquimics (glycemia, total cholesterol and triglycerides) and imagenologhycs (total coronary calcium score and by artery). Results: The extensive coronary artery calci...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Diabetic patients are more likely to have an acute coronary syndrome or even sudden silent death. Among the diabetic population there is the paradox of an early onset of coronary disease and a late diagnosis due to the absence of a striking clinic. Angina in the diabetic patient usually has an atypical presentation. The technique described by Agatston to quantify coronary calcium consists in measuring the total area of calcified coronary plaque in pixels, cut by cut, assigning a score. Coronary artery calcification has been shown to be an excellent measure of atherosclerotic load in epicardial vessels. The calcium in coronary arteries is related to cardiac events in the general population and its quantification is consistently higher in patients with clinic coronary disease. The presence of vascular calcification may provide an additional reason for both the physician and the ...