Synthetic Antioxidants and Its Effects in Ultra Low Concentrations, Probability of Cardio Protection by Membrane Stabilization-Juniper Publishers
JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Oxygen-Sensing Mechanism Oxygen-sensing mechanisms are one of the most important for cell and tissue homeostasis, as well as to adapt to the chronic low-oxygen condition, but intensive production of reactive oxygen species (ROS) can cause cell destruction. Endogenous antioxidant system protects from ROS overproduction, exogenous antioxidants in ultra low concentrations have protective effects too [1]. Detection of ability of biologically active substances (BAS) to modify live systems in ultra low concentration (10-22-10-14Ðœ), is one of the most impressing investments of last decades [2,3]. The specificities of influence of ultra low doses (ULD) of biologically active substances is complex and polymodal dependence of effect on dose; kinetic paradoxes; dependence of reaction on initial characteristics of biological object; «stratification» of effect (there are no effect in average doses,...