Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Brugada syndrome (BrS) is an inherited sodium channelopathy, which can precipitate malignant ventricular arrhythmias and sudden cardiac death. This is a 43-year-old male who presented with ventricular fibrillation cardiac arrest induced by cannabis in the setting of previously undiagnosed BrS. With the increasing prevalence of cannabis use, it is necessary to be aware of its potential adverse cardiovascular effects. This case highlights the diagnostic and clinical challenge of BrS and a raises the issue of cannabis as a potential provoking agent of malignant arrhythmias in BrS. Keywords: Brugada syndrome; Cannabis; Marijuana; Cardiac arrest Introduction Brugada syndrome (BrS) is an inherited sodium channelopathy, which can precipitate malignant ventricular arrhythmias and sudden cardiac death [ 1 ]. Characteristic electrocardiographic f...

  JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Introduction Coronary arteries of anomalous origin are uncommon and encountered in 0.2-1.2% of patients undergoing percutaneous coronary intervention and represent a marked deviation of the normal anatomic pattern [ 1 , 2 ]. An anomalous origin of the right coronary artery (RCA) from the left sinus of Valsalva (LSOV) has been reported in 6-27% of patients with coronary anomalies. Moreover, the anomalous origin of the RCA from the LSOV is associated with early development of coronary artery disease and it can cause sudden cardiac death [ 3 ]. However, PCIs of anomalous right coronary artery (ARCA) from the LSOV pose considerable technical challenges to the interventionalist due to unusual location and course of this anomaly. Still, CTO-PCIs against ARCA from the LSOV require more technical conditions for appropriate back-up support of guiding catheters to overcome problems such as anat...