The Deleterious Effect of Atrial Fibrillation and Its Association with Mortality in Non-Responders to Cardiac Resynchronization Therapy-Juniper Publishers
The
Deleterious Effect of Atrial Fibrillation and Its Association with Mortality in
Non-Responders to Cardiac Resynchronization Therapy by Osmar Antonio Centurion in
Journal of Cardiology & Cardiovascular Therapy in Juniper Publishers
https://juniperpublishers.com/jocct/JOCCT.MS.ID.555556.php
The well known complexity of the
mechanism for developing atrial fibrillation (AF) accounts for the failure and
relative success of the different therapeutic maneuvers in the management of
AF. Despite medical improvements made in recent years, patients with heart
failure (HF) are at increased risk of developing AF [1-3]. AF is known to
worsen the clinical course of HF through multiple mechanisms including rapid
ventricular response, irregularity of ventricular rhythm, loss of organized
atrial contribution to cardiac output, and in some cases, tachycardia-induced
cardiomyopathy. The prevalence of AF, in patients with HF, increases with the
severity of the disease reaching up to 50% in advanced cases. In these patients
with HF, AF is an independent predictor of morbidity and mortality increasing
the risk of death and hospitalization in 76%.
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