Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Congenital heart disease is the most frequent malformation, many cases are complex cyanotic congenital heart defects characterized by low arterial oxygen saturation. Unrepaired intracardiac or extracardiac congenital heart defects which causes a persistent right to left shunt, they are responsible for hypoxemic syndrome, this is a multisystemic disorder affecting various organs and symstems: hematopoietic, central nervous, gastrointestinal, urinary, cardiovascular, Immune, musculoskeletal and endocrine. The objective this review is to explain the pathophysiological mechanisms adapted to the chronic hypoxia, the consequences derived from the affectation in the different systems. The diagnostic approach and management in centers specialized in adults with congenital heart disease. This review was made with articles search sources in databases PubMed, ScienceDirect, OVID, HINARI, S

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Congenital Heart disease affects almost 1% of babies born in the UK, but few receive a genetic diagnosis. Identifying a genetic cause is important for that individual’s healthcare, and that of their family. It enables accurate genetic counselling, including discussion of reproductive choices. Significant advances have been made in identifying genes that are involved in the developing heart and congenital heart disease, and research has moved away from single family studies towards genetic sequencing of large cohorts. This will bring new challenges for clinicians and researchers related to data sharing and incidental findings. In the future, we hope that new treatments can be developed based on our understanding of the complex genetic networks underlying development of the heart. Keywords: Congenital heart disease; Genetics; Inheritance; Chromatin; Sequencing; Syndromic; Non-syn

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract ST segment elevation myocardial infarction (STEMI) is a well described medical emergency with significant strides in medical management drastically improving survival, however its complications are less frequently described. It can be a difficult task to determine the cause of an acute decompensation after successful revascularization of a STEMI. The differential includes a myriad of acute medical and surgical emergencies, including re-occlusion, stent thrombosis, and mechanical dysfunction of the free wall, septum or valves. Among these is the rare and often fatal acquired ventricular septal defect (VSD). A high index of suspicion of this complication is necessary for early recognition to improve survival. We present a case of an 83-year-old male who after 14 days of a hospital admission for STEMI with successful revascularization had an acute decompensation from hypoxemia refra

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract This article reviews and combines different mathematical methods and techniques in order to model the mitral valve of heart and blood fluid movements in the vicinity of the valve. Currently, an echocardiogram is the best thing to study the morphology of the heart mitral valve based on images obtained from ultrasound methods. Utilizing mathematical equations and methods, specific echocardiographic data may provide more detailed, valuable and practical information for physicians. The problem is a tissue-fluid interaction. A 3D mitral valve tissue modeling states a boundary condition to study the blood fluid dynamic around the mitral valve. The body force interacted between the fluid and mitral valve leaflet tissues, combined with the general Lagrangian-Euler equations, gives a fibered model of the mitral valve. This fibered model presents a boundary condition for the solution of

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract This report describes a case of a patient with right-sided pneumothorax presenting with classic electrocardiographic findings such as low voltage, extreme axis deviation to the right and tall R-wave in V1 suggesting right-ventricle overload. Drainage and aspiration were performed stabilizing the patient. Keywords: Pneumothorax; Right-sided pneumothorax; Electrocardiography Introduction Electrocardiogram (ECG) findings such as right axis deviation, QSR abnormalities, T-wave inversions and ST-segment alterations [ 1 ] may lead to misdiagnosis of pneumothorax [ 2 ]. We describe a case of pneumothorax presenting with changes in ECG. Case Report A 74-year-old male was admitted to the emergency department with chest pain 72 hours after a fall. The patient had a past medical h