Juniper Publishers: Coupling Genetic Addiction Risk Score (GARS) and P...

Juniper Publishers: Coupling Genetic Addiction Risk Score (GARS) and P...: Coupling Genetic Addiction Risk Score (GARS) and Pro Dopamine Regulation (KB220) to Combat Substance Use Disorder (SUD) by Kenneth ...

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Intradialytic Hypotension and Left Ventricular Function Improved After Intravenous Levo Carnitine Therapy in a Pediatric Hemodialysis Patient-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Background: The significant decline of endogenous carnitine levels has been well confirmed in a single hemodialysis session. In children, owing to poor tissue stores, and growing demand, a resurgence in carnitine levels may take much longer time. Intradialytic hypotension secondary to carnitine deficiency is commonly due to depressed cardiac function. During hemodialysis, both oral carnitine and intravenous carnitine has been equally effective in adults by reducing the signs and symptoms. However, in children, intravenous carnitine may be more effective in the management of intradialytic hypotension and improving heart function. Case presentation: We report a 9-year-old girl who is a known case of end-stage renal failure secondary to hypoplastic kidneys. Her dialysis is complicated with left ventricular systolic dysfunction, and tertiary hyperparathyroidism for which she und...
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Myocardial Infarction and Rupture of the Left Ventricle After Sexual Intercourse-Juniper Publishers

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Myocardial Infarction and Rupture of the Left Ventricle After Sexual Intercourse by Mercè Subirana-Domènech in Juniper Publishers in Journal of Cardiology & Cardiovascular Therapy A 59 year old caucasian male died after having sex with a prostitute. The medicolegal autopsy reported a sudden death due to hemopericardium tamponade associated with myocardial infarction and coronary artery disease. As a comorbidities we considered the death was related to overweight and type 2 diabetes. Sudden death reported during sexual intercourse has low incidence rates but when it occurs while having extramarital sexual activity, a thorough study of the cause, manner and circumstances of death is required. https://juniperpublishers.com/jocct/JOCCT.MS.ID.555553.php
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Hypertensive Cardiomyopathy: Diagnostic Approach and Clinical Differentiation from Hypertrophic Cardiomyopathy

Abstract Hypertensive Cardiomyopathy (HTN-CM) is a structural cardiac disorder generally accompanied by concentric or eccentric Left Ventricular Hypertrophy (LVH) associated with diastolic or/and systolic dysfunction in patients with persistent systemic hypertension. It occurs in the absence of other cardiac diseases capable of causing myocardial hypertrophy or cardiac dysfunction. Long standing arterial hypertension (HTN) leads to structural and functional myocardial abnormalities resulting in myocardial ischemia, fibrosis, and hypertrophy. HTN-CM is predominantly a disease of impaired relaxation rather than impaired contractility, although subtle myocardial systolic abnormalities could be detected recently by Global Longitudinal Systolic Strain (GLS) Speckle Tracking Echocardiography (STE). Importantly, the accompanying LVH is itself a risk factor for mortality and morbidity and is considered an independent predictor for Sudden Cardiac Death (SCD). Therefore, early d...
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