Coenzyme Q10: The Cardiac Bio-energizer in Cardiovascular Diseases-Juniper Publishers
This systematic review is aimed to identify, evaluate and summarize the role of oral Coenzyme Q10 supplementation in prevention and treatment of cardiovascular diseases (CVD). CoQ10 is concentrated primarily in the cellular mitochondria where it functions as a co-factor transferring electrons from Complex I to Complex II, III ultimately resulting in the formation of energy in the form of ATP. Coenzyme Q10 an endogenous antioxidant declines in our body because of various factors like aging, diseases and use of certain drugs like statins, beta-blockers which exacerbate its deficiency. Deficiency of this important endogenous antioxidant CoQ10 results in energy depleted state. Published data and research have suggested that Coenzyme Q10 an endogenous antioxidant has a potential for being used in the prevention and treatment of CVDs, in particular in Heart failure and Ischemic heart disease. Supplementation with CoQ10 not only corrects the deficiency of CoQ10 by improving t...