Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Background: The significant decline of endogenous carnitine levels has been well confirmed in a single hemodialysis session. In children, owing to poor tissue stores, and growing demand, a resurgence in carnitine levels may take much longer time. Intradialytic hypotension secondary to carnitine deficiency is commonly due to depressed cardiac function. During hemodialysis, both oral carnitine and intravenous carnitine has been equally effective in adults by reducing the signs and symptoms. However, in children, intravenous carnitine may be more effective in the management of intradialytic hypotension and improving heart function. Case presentation: We report a 9-year-old girl who is a known case of end-stage renal failure secondary to hypoplastic kidneys. Her dialysis is complicated with left ventricular systolic dysfunction, and tertiary hyperparathyroidism for which she und...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Introduction: Congenital rubella syndrome (CRS) is a consequence of rubella infection that can occur when the virus is transmitted in utero during maternal primary infection. It still affects 110,000 children around the world. It has a wide spectrum of presentation which ranges from silent viremia to spontaneous abortions, blindness, deafness, congenital heart disease, and mental retardation. Case report: Here, we report a case of CRS in a girl aged 8 years who presented with congenital cataract, severe post ductal coarctation of aorta with patent ductus arteriosus and bilateral sensory neural hearing impairment. Conclusion: We present a case report of congenital rubella syndrome (CRS); though uncommon nowadays, it is still present in India. The main characteristics of our case report were congenital cataract, severe post ductal coarctation of aorta with patent ductu...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Keywords Keywords: Stroke; Coronary artery disease; Paraplegia; Tetraplegia Opinion Spinal cord injury (SCI) is a devastating, life-changing condition causing paralysis and sensory impairment as well as autonomic dysfunction. In addition, evidence documents a state of chronic inflammation in individuals with SCI [ 1 - 4 ]. Importantly, chronic inflammation is a significant cardiovascular disease risk factor. Furthermore, paralysis can lead to a relatively sedentary life style and a consequent reduction in physical work capacity [ 58 ]. Other consequences of inactivity are a higher body weight, a higher percentage of body fat [ 9 , 10 ], skeletal muscle dysfunction [ 11 - 14 ] and a lower forced vital capacity [ 15 - 17 ]. Autonomic dysfunction involves an abnormal and unstable regulation of the of the heart and vasculature [ 18 ]. ...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Background: Idiopathic premature ventricular complexes (PVCs) are considered a benign form of cardiac arrhythmia. However, several reports demonstrated that frequent PVCs were associated with left ventricular (LV) dysfunction, increased LV dimensions and cardiomyopathy. Case Report: A 52-year-old lady with underlying diabetes mellitus, hypertension and dyslipidemia presented with dyspnea and palpitation. Echocardiography showed ejection fraction (EF) of 25% with LV systolic diameter 5.2cm and mild functional mitral regurgitation (MR). Holter revealed 13657 isolated and couplet PVCs which represented 11.2% of total QRS count in 24 hours. Cardiac MRI showed no inducible ischemia, fibrosis, infarction or inflammation. Her baseline 12-lead ECG showed inferior axis PVCs with left bundle branch block morphology. Electrophysiology study using the Carto® 3 System (Biosense Webster, Irv...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Introduction The wearable cardioverter defibrillator (WCD) has recently been introduced as a therapy to reduce mortality in patients presumed to be increased risk for sudden arrhythmic death. Its efficacy appears to be implied by its proven ability to detect and defibrillate VT/VF. However the currently available data on the WCD is non-randomized and comes from several reports of single center experiences, and reviews of post market release, often vendor supported, registry data. In the absence of randomized trials, the effect of the WCD on patient survival cannot be determined. The mere ability to shock terminate VT/VF by the WCD does not suffice to assume survival benefit when used in large patient populations. These severe limitations have been acknowledged in the recent AHA science advisory report [ 1 ], providing a "tentative interim framework" resulting in mostly class II b ...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Hypertension is one the major preventable causes of death and morbidity. The prevalence of hypertension is approximately 30-35% at studies conducted in countries. Today; the role played by hypertension in the development of heart failure and coronary heart disease and the benefits of primary prevention with effective treatment have been clearly demonstrated. The significance of treatment of hypertension in terms of secondary prevention has also been established in patients with heart failure and coronary heart disease. By the current guidelines, hypertension treatment goals has been individualized and specific patient groups have also been amide to provide the highest benefit from therapy. Early identification and effective treatment of hypertension therefore has vital importance for both primary and secondary prevention. Keywords: Hypertension; Coronary artery disease; Heart f...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract There is an old saying that health is wealth. Every organ of a human being is important. But heart is the most sensitive organ. Increased blood pressure and blockage of arteries are the two important symptoms of the heart problem. The present article is intended for the benefit of the common man to guide him to maintain a healthy heart, reducing his chances to fall ill and to seek medical remedies. Keywords: Guidance for healthy heart Opinion This article is concerned mainly with the problems of the healthy functioning of the most important and the sensitive organ, the heart of a human being. At the outset, I wish to assert that I am not a cardiologist, nor a doctor with a medical degree. However, I am a qualified scientist of long standing with knowledge and experience of several fields of the modern man. It is believed that ...