Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Metadichol®, [1] a nano formulation a mixture of long chain alcohols that is present in many foods like rice and sugar cane and is derived from the waste of the sugar cane industry. It is a renewable resource. Most of the clinical data in literature is a: non-nano formulation either a tablet or capsule which have not shown any efficacy. Given its safety profile, we carried out a small open-label pilot study on diabetic patients with hypertension who had in additional co-morbidities such as dyslipidemia, obesity, and hypertension. None of them were on any hypertensive medication. Our studies on patients for 60 weeks in an open-label study @20mg per day showed that it is possible to bring about improvements in Systolic and diastolic pressure in addition to CRP, VLDL, HDL, Triglycerides and waist circumference reduction and reduction in insulin resistance. Interestingly Vitamin C level...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Objective: This study was conducted to outline the clinical profile and outcomes of infective endocarditic (IE). It provides a contemporary picture of the presentation, etiology and outcomes of IE. Methods: A total of 97 consecutive cases of definitive IE who met the modified Duke’s definitive criteria were included in the study. We analysed their clinic-epidemiologic features and outcomes. Results: The mean age was 34.8±14.6 years with male preponderance (57.7%). Rheumatic heart disease (RHD) (29.8%) was the commonest underlying cause followed by congenital heart disease (CHD) (20.6%). Fever as the main clinical feature was seen in 95.8%. About 61.8% of patients were in New York Heart Association (NYHA) class II. Blood culture was positive in 44.3% with commonest organisms being Staphylococcus aureus (10.3%) and Streptococci viridians (9.3%). Most common valve involvement was m...

Madaj Paul M | A Review: Garlic Effects on the Cardiovascular System Abstract Coronary Artery Disease (CAD) is one of the leading causes of morbidity and mortality in the world. Detection as well as modification of risk factors for cardiovascular disease (CVD) has been the topics research over several decades. Multiple drugs have been studied and used in clinical practice with people seeking “natural” alternatives. When evaluating for optimal treatment options and the multiple risk factors associated CAD (e.g. diabetes, hypertension, etc.), garlic can play a prominent role. Studies have shown promising results in treating hypertension, altering the lipid profile, prevention and even treatment of coronary atherosclerosis and its systemic anti-oxidant properties. Garlic also has positive effects outside the cardiovascular system (e.g. immune system). It can be used stand-alone or as an adjunct to current medical therapy. No clinically significant side effects have been r...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Introduction In the continuously evolving efforts to provide optimum revascularization for high risk Critical Limb Ischemia patients, vascular surgeons around the world have widely adopted hybrid approach. This combination of the advantages of open and endovascular techniques allows the implementation of tailored complex multi-level reconstruction plans usually within a single setting [1-3]. What started over 40 years ago, with the combination of simple iliac angioplasty and femoro-femoral bypass [4] is gradually increasing in complexity & becoming a widely accepted therapeutic option. Furthermore, the increasing sophistication of minimally invasive endovascular techniques with successful treatment of multi-segmental lesions has contributed to a reduced morbidity & duration of hospital stay when Hybrid revascularizations are performed [5]. The final benefit thus is full revascu...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Present Status of Acute MI Patients in Japan Approximately 40,000 patients die from acute myocardial infarction (MI) in Japan every year according to the data from Vital Statistics 2014 reported by the Ministry of Health, Labor, and Welfare. However, the number of patients hospitalized due to acute MI is about 69,000/year, and the in-hospital mortality of those patients is below 10% according to the data from The Japanese Registry of all cardiac and vascular Disease (JROAD) reported by the Japanese Circulation Society. Therefore, approximately 34,000 patients with acute MI die before hospitalization every year and approximately 40% of acute MI patients die after onset mainly before hospitalization. Judging from these data, we should pay more attention to how to prevent acute MI rather than to how to treat acute MI patients in hospital to save their lives. Proc...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Introduction Dysphagia lusoria is a sporadic condition that causes difficulty swallowing. The symptoms are attributed to an aberrant right subclavian artery that has a retroesophageal course leading to vascular compression of the esophagus. Dysphagia lusoria is an uncommon anomaly and even rarer cause of symptoms. However, when symptomatic and occurring in conjunction with similar presenting conditions, it can create a diagnostic and treatment challenge [1]. Case Report A 62-year-old female with a medical history significant for coronary artery disease and gastritis presented to our hospital on multiple occasions complaining of chronic nausea, dyspnea, chest pain and dysphagia. Physical examination was often unrevealing with the exception of hypertensive blood pressure. Laboratory investigation often included completeblood cell count, complete metabolic panel, serial troponi...

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Active infective endocarditis (AIE) is major problem especially for patients with prior valve intervention or device implantation. We present a 77-year-old patient suffering from AIE 14 months after transcatheter-implanted aortic valve (TAVI). The heart team considerated TAVI by increased operative risk, Euro SCORE of 10.42%, including sever pulmonary hypertension, chronic obstructive pulmonary disease, insulin depending diabetes mellitus, chronic renal failure and polyneuropathy. Post-interventional, the patient suffered from an aneurysm spurium. During follow-up, the patient underwent dental treatment and afterwards developed 39°C fever und blood culture showed repeatedly Escherichia Coli. Echocardiographic examination showed a new paravalvular leakage with limited vegetation at the TAVI. The heart team decided, although a Euro SCORE of 63.57%, appropriate antimicrobial...