Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Degeneration of bioprosthesis may occur in elderly and frail patients with an extremely high risk for redo cardiac surgery. Transcatheter valve-in-valve procedures represent a valuable treatment option in high-risk patients [ 1 , 2 ]. However incidental findings may contraindicate the transcatheter procedure. We describe the original case of a patient who was scheduled for transapical mitral valve-in-valve, but due to a left atrial mass underwent mini-invasive surgery with successful direct mitral valve-in-valve delivery and excision of the mass. Keywords: TAVI; Transcatheter; Mitral; Valve-in-valve; Bioprosthesis failure; Minimally invasive surgery Introduction Degeneration of bioprosthesis may occur in elderly and frail patients with an extremely high risk for redo cardiac surgery. Transcatheter valve-in-valve procedu

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Background: Double or triple antiplatelet therapy is a guideline mandated therapy for patients who undergo Percutaneous Coronary Intervention (PCI). However, there exists inter-individual variability in drug response to the antiplatelet agents leading to recurrent thrombotic events. We sought to study the efficacy and variability of thienopyridines (clopidogrel and prasugrel), ticagrelor and triple antiplatelet therapy in Post-PCI percutaneous coronary intervention (PCI) patients using AggreGuide A-100 platelet aggregometer, a point-of-care-test (POCT) device using laser light scattering technique. Methods: It was a single-centred prospective trial, included 405 patients who underwent PCI. Platelet reactivity was assessed by grading of platelet activity index (PAI) and considered as high on treatment platelet reactivity (HTPR) if PAI >5. Results: Patients on clopido

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Introduction: Double chambered right ventricle (DCRV) is a rare congenital anomaly in which right ventricle (RV) is divided into two chambers by anomalous muscle band (AMB), a proximal high-pressure and distal low pressure chamber. Most of DCRV cases present during childhood, however, less commonly manifest in adulthood because of the nonspecific nature of symptoms leading to a delayed diagnosis. However, there are very few studies of DCRV in adults with regard to clinical features, hemodynamic data, treatment and prognosis, hence these are assessed in this current study. Methods: A total of 10 adult patients (age ≤18 years) diagnosed as DCRV by echocardiograpy and cardiac catheterization in our hospital from January 2008 to December 2015 were included. Nine patients had a history of a known heart disease since childhood (PM-VSD) with one patient being operated at the age

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Acute pulmonary embolism (APE) is a cardiovascular emergency that without prompt clinical diagnosis and treatment may result in fatal outcomes. Indeed, the symptoms can be quite non-specific often causing clinical dilemma as well as potentially at risk of misdiagnosing on the initial presentation. More specifically, the electrocardiographic (ECG) manifestation of APE can be diverse from normal to sinus tachycardia with or without features of acute right heart strain. We present an unusual case of APE presented with the pattern of acute ST-elevation on the 12-lead ECG mimicking acute myocardial infarction; thereby discussing the clinical dilemma which arose with this case as well as all the potentially and relevant differential diagnosis for the presentation. Keywords: ST- elevation; Acute pulmonary embolism; Acute myocardial infarction

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract Many forms of left-sided heart disease can be associated with pulmonary hypertension (PH-LHD) which typically indicates more advanced heart disease, more severe symptoms and worse prognosis. Mitral valve disease, both insufficiency and stenosis, can lead to the downstream development of PH. Current guidelines suggest that the most effective therapy for severe mitral valve disease (stenosis and/or regurgitation) is surgical intervention, yet in some cases, the operative outcome bordered by high perioperative risks. Patients and methods: Data for this study included 680 cases of adult patients underwent first-time mitral valve replacement. All patients of the study were divided into 2 groups: those who had PASP 50-80mmHg categorized as severe pulmonary hypertension=(group I) and those who had PASP above 80mmHg Categorized as extreme PH=( group II). Results: Echo-cardio graphic data