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The New Emerging Science of Cardio-Oncology-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Opinion Cardio-Oncology is a new science, wide, and involves Cardiologists, Oncologists, Pathologists, Hematologists, Pharmacologists and Nurses. There are some principles we should all know in dealing with this science to get the best results and benefits to our patients: Cardiologists should know some Oncology basics and Oncologists to know some Cardiology basics. Cancer itself without administration of cancer therapy can cause Cardio toxicity and lead to left ventricular dysfunction and heart failure and here we need also Cardiologists to stand beside the Oncologists. We have to know that we are dealing with two types of individuals, those with an established cardiovascular diseases and going to receive cancer medications which may worsen their CV status, and the group which is without obvious cardiovascular disease but will receive cancer drugs that may cause them develop a new CV disea

Sequential Devices Occlusion of Post-Surgical Ascending Aorta Pseudoaneurysms in a Child, Case Report-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Pseudoaneurysm of ascending aorta is an infrequent but well recognized and potentially fatal complication after cardiac surgery. This complication can develop early and late after surgery with variable presentation. We are reporting a case of pseudoaneurysm of ascending aorta following cardiac surgery at the site of cardioplegia needle and aortic cannulation that were successfully managed by percutaneous catheter based-placement of two devices in two occasions with fluoroscopic and two and three dimensional transesophageal echocardiography (TEE) guidance. The first device was an Amplatzer duct occluder type II at the cardioplegia needle site. The other aneurysm was located at the aortic cannulation site and was closed using an Amplatzer atrial septal occluder size 5mm. An immediate post procedure TEE and a Transthoracic Echocardiography at hospital discharge showed no residual le

The Evolution of Improved Diagnosis of Coronary and Vascular Disorders-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Opinion The diagnosis of myocardial infarction leaped forward when Arthur Karmen [ 1 ] devised the spectrophotometric method for measuring aspartame aminotransferase (AST) in serum in 1954. Prior to this, there was only the electrocardiogram and characteristic chest pain. In these studies, Karmen [ 1 ] demonstrated that acute myocardial infarct and also hepatic necrosis can be determined by measuring the serum elevation of either AST or on the other hand, alanine aminotransferase. He also measured the NADH linked lactate and malate dehydrogenases, of which Kaplan [ 2 ] found had enzymes, of which H-type LD was used for the diagnosis of myocardial infarct and the M-type for the diagnosis of hepatic or muscle injury. The H-type LD was elevated to a peak on the second day after infarct. But these tests were followed by creatine kinase (CK) and the CK-MB isoenzyme, which had an earlier rise t

Myocarditis in Anti-Synthesise Syndrome-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Case Report A previously healthy 36-year-old-man presented with polyarthralgias, fever and asthenia and weight loss. He denied any muscular weakness or dyspnoea. On physical examination, the following were present: per orbital lilaceous skin rash (heliotrope), symmetric mauls and papules on the dorsal aspect of metacarpohalangeal joints (Gorton’s papules) and bilateral arthritis in proximal interphalangeal joints. No weakness on the proximal or distal upper and lower limbs. Laboratory studies showed elevated ESR and positive anti-glycol (EJ)- tRNA-synthetaseantibodie and anti-MDA5. However, creating kinas and idolise were normal. Chest high-resolution computed tomography revealed non-defined opacities in both lungs (mainly in posterior and basal segments) and interlobular sepal thickening. A suspicious of depressed right ventricular ejection fraction was found on the echocardiogram arose.

Sudden Heart Pathology-a New Research Hipotesys-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Keywords Keywords: Cardiology; Heart disease; Diagnostic systems Introduction We can see that heart is usually studied using many diagnostic strategies and under different Mechanism as functions, electric activity, receptorial, imaging, instrumental test, genetic profile, exercise tests, biopsy and so on. But what we can see is that until today in not possible to prevent some unexpected death. So we can think that perhaps we need more diagnostic test to right consider this aspect. Can we use innovative methods to introduce more useful systems? In ischemic condition some test can help to detect the residual heart capacity but can we test in the same way the heart biochemical-metabolic status or pharmacological profile? In a recent case we have see that in a transplant heart procedure was used an organ by a patient death Due to cerebral damage after a heart at

Acute Inferior Pseudo Infarction Pattern in a Patient with Hyperosmolar Hyperglycemic State-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY Abstract ST elevation myocardial infarction (STEMI) is a medical emergency that requires timely revascularization for better outcomes. However, other causes of ST elevation (STE) should always be considered in the differential diagnosis. Of these causes, diabetic ketoacidosis has been reported in the past, even in normokalemic patients, however, to our knowledge, hyperosmolar hyperglycemic state (HHS) has never been reported to be associated with ST elevations. Here, we present a case of HHS in a patient who had inferolateral STE on EKG with normal coronary angiogram Keywords: ST elevation myocardial infarction; Hyperosmolar hyperglycemic state Introduction ST elevation myocardial infarction (STEMI) is a medical emergency, and the earlier the revascularization is achieved via thrombolysis or percutaneous coronary intervention, the better the prognosis. However,

The Scope of Cardiac Surgery at a National Cardiothoracic Center of Excellence (NCTCE) in Nigeria, a 3-Year Review-Juniper Publishers

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JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract The heart with its intrinsic and indispensable function is a vital organ in the human body. Surgical management of diseases affecting it was initially thought to be incompatible with life. Surgeons who desired the respect of their colleagues were barred from operating on the heart, on the ground that human knowledge is very limited in that area. This notion was however changed in 1893 when laceration in the left ventricle was successfully repaired at Chicago Provident Hospital in USA. Three years later, the same feat was successfully reproduced several times in Fran K furt Germany. Also by 1938 in Boston Children Hospital, Massachusetts, USA, Robert Gross successfully interrupted a PDA in a 7 year old child. This was followed by successful repair of coarctation of the aorta and the famous blue baby operation, all in 1944, thus unequivocally, proving that successful operation on t