Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Introduction Coronary Artery Aneurysm (CAA) is defined dilatation of a coronary artery exceeding more than 1.5 fold of the normal vessel diameter. If there is diffuse dilatation in coronary arteries that involves 50% or more of the length of the artery, it is named as coronary ectasia. In addition, the Committee of the American Heart Association has termed "giant aneurysm" if the aneurysm is greater than 8mm (or exceeding more than 4 fold of the normal vessel). Even atherosclerosis is the most common etiology, Kawasaki Disease, inflammatory arterial disease [Polyarthritis Nodosa (PAN), Syphilis, Takayasu Arteritis and Behcet's Disease], Connective Tissue Disease (CTD) and coronary artery revascularization procedures can be responsible for other cases. Treatment of a CAA is important because it may predispose ischemia, myocardial infarction, distal embolization due to thrombus...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Background: Kawasaki Disease is an acute febrile illness of early childhood. It is seen worldwide with the highest incidence occurring in Asian children under 5 years of age and in the male gender. Major sequelae involve the coronary arterial system, leading to aneurysms and occlusions. Case: This is a case of an 11-year-old male, who was diagnosed with Atypical Kawasaki Disease in 2007, for which Gamma Globulin and Aspirin were given. Diagnostic imaging showed severe three-vessel coronary artery disease with chronic total occlusion of the right coronary and left mid-circumflex artery and an aneurysmal dilation of the proximal left anterior descending artery measuring 12.4x11.3x25.5mm. He is the first paediatric patient in the Philippines who underwent quadruple coronary bypass and grafting. Conclusion: This case features the significance of early diagnosis and treatment of...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Keywords: Keywords: Adenosine; Tachycardia; Paradoxical response Introduction Adenosine bolus administration is extremely valuable in the first approach to narrow-QRS tachycardia. We present two cases in which this strategy leaded to an unexpected effect. We focus on the importance of knowing this effect of the adenosine in this setting so that the maneuver is performed in an appropriate place and carried out by trained staff. Case Report Case A 73-year-old lady with hypertension, diabetes and dyslipidemia referred progressive dyspnea for two months. On physical examination, no murmurs, arrhythmia or crackles were audible. Cardiomegaly was present on the x-ray chest. ECG is performed ( Figure 1 ): narrow QRS tachycardia with low voltage. Then, a bolus of 6mg of adenosine is administered intravenously twice as a diagnostic and...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Background: Asymmetric septal hypertrophy is the most prevalent form of hypertrophic cardiomyopathy. The aim of this series of cases is to demonstrate the measures performed by perioperative transesophageal echocardiography (TEE) during myectomy procedures. Methods: A retrospective analysis of the echocardiography exams from patients who underwent myectomy procedure from January 2015 to January 2017 was developed. Were excluded patients who underwent emergency surgeries, combined surgery and patients who had already septal coronary artery alcoholization. Results: A total of 4 patients were evaluated in the period from 2015 to 2017. They were all women, ASA 3 with a mean age of 61±8,7 years old. The left ventricle outflow tract (LVOT) peak gradient pre-CPB was 114,4±50,6mmHg and post-CPB was 42,4 46,3mmHg. The LVOT mean gradient pre-CPB was 52,4±19,9mmHg and post-CPB was 21...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Opinion Doxorubicin (DOX) as a 40 year-old anthracycline antibiotic is a potent antineoplastic agent extensively used in the treatment of several malignancies [ 1 ]. Nevertheless, its clinical application carries the risk of serious non-target tissues toxicities, in particular cardiomyopathy, which manifests as life-threatening congestive heart failure [ 2 ]. It has been suggested that several mechanisms including reactive oxygen species over-generation, cardiomyocytes apoptosis, membrane-associated ion pumps dysfunction and topoisomerase II isoforms inhibition may be involved in DOX-induced cardiotoxicity [ 3 - 5 ]. To date, many studies have been carried out using adjunctive therapy to counteract DOX-evoked cardiac damages and it has been proposed that development of alternative cardioprotective strategies for management of DOX-related cardiotoxicity is inevitable [ 6 - 8 ]. However,...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract In this report, we present a case of young male with Erdheim Chester Syndrome, who presented with dyspnea due to recurrent large pericardial effusion and impending tamponade. The patient underwent percutaneous pericardiocentesis and started on steroid, interferon alpha and immunosuppressive treatment with subjective improvement of his symptoms and rate of pericardial fluid re accumulation. This report will give an updated review of the syndrome. Introduction Erdheim Chester Disease (ECD) is a Non- Langerhans histiocytic disorder without a clear cut etiology [ 1 , 2 ]. Non- Langerhans histiocytic disorders are named as such due to the fact that the disorder or the cells affected are derived from cells otherthan that of Langerhans- typically of monocytic/ macrophagic origin [ 3 ]. Erdheim Chester Disease causes inflammation followed by invasion and ...