Juniper Publishers Journal of Cardiology and Cardiovascular Therapy

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract Background: Meticulous risk stratification for contrast-induced nephropathy (CIN) is important for patients with ST-segment elevation myocardial infarction (STEMI) and treated with primary percutaneous coronary intervention (PPCI). Aim of the work: To compare between different risk scores for predicting contrast induced nephropathy and short outcome after primary percutaneous coronary intervention in patients with ST elevation myocardial infarction. Material and methods: We prospectively enrolled 100 patients who presented with STEMI and treated with Primary PCI (PPCI). Mehran, Gao, Chen, ACEF or AGEF (age, serum creatinine, or glomerular filtration rate, and ejection fraction); and GRACE (Global Registry for Acute Coronary Events) risk scores were calculated for each patient. The predictive accuracy of the 6 scores for CIN, in-hospital death and major adverse clinical events ...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract We report a case of successful combined percutaneous intervention in a middle aged female with coronary artery disease (CAD) and atrial septal defect (ASD). The case demonstrates the feasibility and safety of performing combined PTCA and ASD device closure in selected patients. Successful combined procedure obviates the need for major surgery and repeated hospitalizations and an effective alternative for patients at high surgical risk. Introduction Coronary artery disease is the leading cause of death worldwide. In contrast to the trend seen in developed countries, mortality from CHD is expected to increase in developing countries, from an estimated 9 million in 1990 to a projected 19 million by 2020 [1,2]. Percutaneous transluminal coronary angioplasty (PTCA) is the established standard treatment modality for patients with symptomatic CAD and the n...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Background CTOs can occur acutely and go unrecognized, as silent clinical events, but probably in more instances than not, they occur gradually over time. Often the area of the myocardium that is subtended by the totally occluded vessel is still very viable and functional despite having an occluded artery, because over time, collaterals have developed to keep the heart tissue alive. However, the collaterals have not been shown to supply enough blood and oxygen required when the demand of the heart muscle increases. Total re- vascularization and restoration of normal ante-grade flow can be very important for many patients with chronic total occlusion (CTO) and attributable symptoms, ischemia, and/or ventricular dysfunction/ dysrhythmia. Technical success remains lower for CTO PCI than for PCI of non-CTO lesions and remains a major impediment to optimally managing patients with coronary ...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract The occurrence of acute coronary events in the setting of hypersensitivity reactions following an allergic insult defines the Kounis-Zavras syndrome that was described for the first time by Pfister in 1951 and published as the first description of allergic angina syndrome by Kounis and Zavras in 1991. Since this topic has not been discussed in the international recommendations for cardiology, this review of Kounis-Zavras syndrome aims to provide an update on this rare clinical entity as well as to highlight the particularity and the special features of how to manage this syndrome. Keywords: Kounis-Zavras syndrome; Myocardial ischemia; Allergy; Coronary spasm; Management Introduction Kounis syndrome refers to allergic acute myocardial ischemia in relation with release of inflammatory mediators by activated mast cell leading to coronary artery spasm...

JUNIPER PUBLISHERS - OPEN ACCESS JOURNAL OF CARDIOLOGY & CARDIOVASCULAR THERAPY   Abstract A double inlet single ventricle is a congenital heart malformation in which both atria are connected to a common or dominant ventricle. It's a rare condition that accounts for about 1 to 2% of all congenital heart defects at birth. Prognosis without surgical intervention is considered to be poor, and survival into the adulthood is unusual. A non invasive cardiac imaging (like echocardiography) play major role in diagnosis, assessment of ventricular function and atrioventricular valves and detection of complications in pre and post operative period after a palliative or definitive surgery. A cardiac catheterization will usually be performed to evaluate defects, associated abnormalities and the amount of blood that is mixing. Several surgical options are available for this condition. We report the case of a 28 years old man who has type A of Van Praagh's classification of si...